Evolution of Haptoglobin Concentration in Serum during the Early Phase of Acute Myocardial Infarction

Peer Reviewe

Harmonic analysis and hypercomplex function theory in co-dimension one

Fundamentals of a function theory in co-dimension one for Clifford algebra valued functions over ℝn+1 are considered. Special attention is given to their origins in analytic properties of holomorphic functions of one and, by some duality reasons, also of several complex variables. Due to algebraic peculiarities caused by non-commutativity of the Clifford product, generalized holomorphic functions are characterized by two different but equivalent properties: on one side by local derivability (existence of a well defined derivative related to co-dimension one) and on the other side by differentiability (existence of a local approximation by linear mappings related to dimension one). As important applications, sequences of harmonic Appell polynomials are considered whose definition and explicit analytic representations rely essentially on both dual approaches.The work of the first, second and fourth authors was supported by Portuguese funds through the CIDMA - Center for Research and Development in Mathematics and Applications, and the Portuguese Foundation for Science and Technology (“FCT-Fundação para a Ciência e Tecnologia”), within project PEst-OE/MAT/UI4106/2013. The work of the second author was supported by Portuguese funds through the CMAT - Centre of Mathematics and FCT within the Project UID/MAT/00013/2013

Hilbert transforms in Clifford analysis

The Hilbert transform on the real line has applications in many fields. In particular in one–dimensional signal processing, the Hilbert operator is used to extract global as well as instantaneous characteristics, such as frequency, amplitude and phase, from real signals. The multidimensional approach to the Hilbert transform usually is a tensorial one, considering the so-called Riesz transforms in each of the cartesian variables separately. In this paper we give an overview of generalized Hilbert transforms in Euclidean space, developed within the framework of Clifford analysis. Roughly speaking, this is a function theory of higher dimensional holomorphic functions, which is particularly suited for a treatment of multidimensional phenomena since all dimensions are encompassed at once as an intrinsic feature

Introductory clifford analysis

In this chapter an introduction is given to Clifford analysis and the underlying Clifford algebras. The functions under consideration are defined on Euclidean space and take values in the universal real or complex Clifford algebra, the structure and properties of which are also recalled in detail. The function theory is centered around the notion of a monogenic function, which is a null solution of a generalized Cauchy–Riemann operator, which is rotation invariant and factorizes the Laplace operator. In this way, Clifford analysis may be considered as both a generalization to higher dimension of the theory of holomorphic functions in the complex plane and a refinement of classical harmonic analysis. A notion of monogenicity may also be associated with the vectorial part of the Cauchy–Riemann operator, which is called the Dirac operator; some attention is paid to the intimate relation between both notions. Since a product of monogenic functions is, in general, no longer monogenic, it is crucial to possess some tools for generating monogenic functions: such tools are provided by Fueter’s theorem on one hand and the Cauchy–Kovalevskaya extension theorem on the other hand. A corner stone in this function theory is the Cauchy integral formula for representation of a monogenic function in the interior of its domain of monogenicity. Starting from this representation formula and related integral formulae, it is possible to consider integral transforms such as Cauchy, Hilbert, and Radon transforms, which are important both within the theoretical framework and in view of possible applications

Segal-Bargmann-Fock modules of monogenic functions

In this paper we introduce the classical Segal-Bargmann transform starting from the basis of Hermite polynomials and extend it to Clifford algebra-valued functions. Then we apply the results to monogenic functions and prove that the Segal-Bargmann kernel corresponds to the kernel of the Fourier-Borel transform for monogenic functionals. This kernel is also the reproducing kernel for the monogenic Bargmann module.Comment: 11 page

q-deformed harmonic and Clifford analysis and the q-Hermite and Laguerre polynomials

We define a q-deformation of the Dirac operator, inspired by the one dimensional q-derivative. This implies a q-deformation of the partial derivatives. By taking the square of this Dirac operator we find a q-deformation of the Laplace operator. This allows to construct q-deformed Schroedinger equations in higher dimensions. The equivalence of these Schroedinger equations with those defined on q-Euclidean space in quantum variables is shown. We also define the m-dimensional q-Clifford-Hermite polynomials and show their connection with the q-Laguerre polynomials. These polynomials are orthogonal with respect to an m-dimensional q-integration, which is related to integration on q-Euclidean space. The q-Laguerre polynomials are the eigenvectors of an su_q(1|1)-representation

Urinary myeloid IgA Fc alpha receptor (CD89) and transglutaminase-2 as new biomarkers for active IgA nephropathy and henoch-Schönlein purpura nephritis

Background: IgA nephropathy (IgAN) and Henoch-Schönlein purpura nephritis (HSPN) are glomerular diseases that share a common and central pathogenic mechanism. The formation of immune complexes containing IgA1, myeloid IgA Fc alpha receptor (FcαRI/CD89) and transglutaminase-2 (TG2) is observed in both conditions. Therefore, urinary CD89 and TG2 could be potential biomarkers to identify active IgAN/HSPN. Methods: In this multicenter study, 160 patients with IgAN or HSPN were enrolled. Urinary concentrations of CD89 and TG2, as well as some other biochemical parameters, were measured. Results: Urinary CD89 and TG2 were lower in patients with active IgAN/HSPN compared to IgAN/HSPN patients in complete remission (P < 0.001). The CD89xTG2 formula had a high ability to discriminate active from inactive IgAN/HSPN in both situations. : CD89xTG2/proteinuria ratio (AUC: 0.84, P < 0.001, sensitivity: 76%, specificity: 74%) and CD89xTG2/urinary creatinine ratio (AUC: 0.82, P < 0.001, sensitivity: 75%, specificity: 74%). Significant correlations between urinary CD89 and TG2 (r = 0.711, P < 0.001), proteinuria and urinary CD89 (r = -0.585, P < 0.001), and proteinuria and urinary TG2 (r = -0.620, P < 0.001) were observed. Conclusions: Determination of CD89 and TG2 in urine samples can be useful to identify patients with active IgAN/HSPN

Radial and angular derivatives of distributions

When expressing a distribution in Euclidean space in spherical coordinates, derivation with respect to the radial and angular co-ordinates is far from trivial. Exploring the possibilities of defining a radial derivative of the delta distribution 8{x) (the angular derivatives of S(x) being zero since the delta distribution is itself radial) led to the introduction of a new kind of distributions, the so-called signumdistributions, as continuous linear functionals on a space of test functions showing a singularity at the origin. In this paper we search for a definition of the radial and angular derivatives of a general standard distribution and again, as expected, we are inevitably led to consider signumdistributions. Although these signumdistributions provide an adequate framework for the actions on distributions aimed at, it turns out that the derivation with respect to the radial distance of a general (signum)distribution is still not yet unambiguous